Model NO.: 700874-72-2
Product Name: Ly2157299
CAS No.: 700874-72-2
Mf: C22h19n5o
MW: 369.42
Delivery by: DHL, TNT, FedEx, Hkems, UPS, etc
Export Markets: Global
Trademark: NEWBIO
Transport Package: Aluminum Foil Bags
Specification: SGS
Origin: China
HS Code: 0000000000
Model NO.: 700874-72-2
Product Name: Ly2157299
CAS No.: 700874-72-2
Mf: C22h19n5o
MW: 369.42
Delivery by: DHL, TNT, FedEx, Hkems, UPS, etc
Export Markets: Global
Trademark: NEWBIO
Transport Package: Aluminum Foil Bags
Specification: SGS
Origin: China
HS Code: 0000000000
Chemical Information:
Â
Product Name |
|
Molecular Formula |
C22H19N5O |
Molecular Weight |
369.42 |
Storage |
Store at -20°C |
Targets |
CXCR4 |
IC50 |
44 nM |
Dosage |
5 mg/kg |
Â
Stability |
3 years  - 20 ºC powder
6 months  -80 ºC dissolved in a solvent
|
Solubility |
Soluble in DMSO > 10 mM |
General tips |
For obtaining a higher solubility , please warm the tube at 37 ºC and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20ºC for several months. |
Shipping Condition |
Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
|
Details:
Â
Synonyms:LY 2157299;4-[5,6-Dihydro-2-(6-methyl-2-pyridinyl)-4H-pyrrolo[1,2-b]pyrazol-3-yl]-6-quinolinecarboxamide;6-QuinolinecarboxaMide, 4-[5,6-dihydro-2-(6-Methyl-2-pyridinyl)-4H-pyrrolo[1,2-b]pyrazol-3-yl]-;4-[2-(6-Methyl-2-pyridinyl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]-6-quinolinecarboxaMideorLY2157299;Galunisertib,LY2157299;4-(2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline-6-carboxamide;4-[5,6-Dihydro-2-(6-methyl-2-pyridinyl)-4H-pyrrolo[1,2-b]pyrazol-3-yl]-6-quinolinecarboxamide LY 2157299;LY2157299,Galunisertib
 Â
Description:LY2157299 is a potent inhibitor of TGFβ receptor I (TβRI) with IC50 of 56 nM.
Â
Â
Application:
Â
LY2157299 induced a 70% decrease in phosphorylated Smad (pSmad) for both types of cell lines. The time at which pSmad recovered 80% of baseline was approximately 6 h after administration.
Â
Â
Notification:This compound is used only for research and not for human trials!
Other Small Molecular API:
Â
AZD9291 |
1421373-65-0 |
E7080 |
417716-92-8 |
Afatinib diMaleate |
439081-18-2 |
XL184Â S-MALATE |
1140909-48-3 |
Crizotinib |
877399-52-5 |
Axitinib |
319460-85-0 |
WZ4002 |
1213269-23-8 |
Vandetanib |
443913-73-3 |
Sunitinib |
557795-19-4 |
Regorafenib |
755037-03-7 |
Imatinib |
152459-95-5 |
Foretinib |
849217-64-7 |
trametinib |
871700-17-3 |
Tivozanib |
475108-18-0 |
Pelitinib |
257933-82-7 |
Cediranib |
288383-20-0 |
Selumetinib |
606143-52-6 |
Tozasertib |
639089-54-6 |
CapMatinib |
1029712-80-8 |
Amuvatinib |
850879-09-3 |
Lestaurtinib |
111358-88-4 |
Brivanib |
649735-46-6 |
Â
1.The parcels will be sent within 24 hours once the order is verified.
2.Packaging is fully in accordance with customer demand.
3.There will be discounts whether you are an old customer or not.
To your satisfiction, here are our advantages
1.High quality and competetive price
1)we can offer coa certificate and official invoice.
2)we are manufacturer with own lab and factory, can provide high quality products with factory price.
3)products purity is test by our quality department strictly before sending, and you can also ask the third testing organization come and inspect, such as (sgs/ cti/ its), only after your confirmation will we send it out to you.
2.Fast and safe delivery
1)products can be sent out in 24 hours after payment.Tracking number available, fixed service person are 7x24h for you to contact.
2) secure and discreet shipment.Various transportation methods for your choice, like dhl/ups/tnt/fedex/sf-express.
3)customs pass and satisfied rate >99%.
4)for hot sale products we have stock in there for transferring.
3 we have clients throughout the world
1) professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2) market feedback and goods feedback will be appreciated, meeting customers' requirement is our responsibility.
3) high quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.
Chemical Information:
Â
Product Name |
|
Molecular Formula |
C22H19N5O |
Molecular Weight |
369.42 |
Storage |
Store at -20°C |
Targets |
CXCR4 |
IC50 |
44 nM |
Dosage |
5 mg/kg |
Â
Stability |
3 years  - 20 ºC powder
6 months  -80 ºC dissolved in a solvent
|
Solubility |
Soluble in DMSO > 10 mM |
General tips |
For obtaining a higher solubility , please warm the tube at 37 ºC and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20ºC for several months. |
Shipping Condition |
Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
|
Details:
Â
Synonyms:LY 2157299;4-[5,6-Dihydro-2-(6-methyl-2-pyridinyl)-4H-pyrrolo[1,2-b]pyrazol-3-yl]-6-quinolinecarboxamide;6-QuinolinecarboxaMide, 4-[5,6-dihydro-2-(6-Methyl-2-pyridinyl)-4H-pyrrolo[1,2-b]pyrazol-3-yl]-;4-[2-(6-Methyl-2-pyridinyl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]-6-quinolinecarboxaMideorLY2157299;Galunisertib,LY2157299;4-(2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline-6-carboxamide;4-[5,6-Dihydro-2-(6-methyl-2-pyridinyl)-4H-pyrrolo[1,2-b]pyrazol-3-yl]-6-quinolinecarboxamide LY 2157299;LY2157299,Galunisertib
 Â
Description:LY2157299 is a potent inhibitor of TGFβ receptor I (TβRI) with IC50 of 56 nM.
Â
Â
Application:
Â
LY2157299 induced a 70% decrease in phosphorylated Smad (pSmad) for both types of cell lines. The time at which pSmad recovered 80% of baseline was approximately 6 h after administration.
Â
Â
Notification:This compound is used only for research and not for human trials!
Other Small Molecular API:
Â
AZD9291 |
1421373-65-0 |
E7080 |
417716-92-8 |
Afatinib diMaleate |
439081-18-2 |
XL184Â S-MALATE |
1140909-48-3 |
Crizotinib |
877399-52-5 |
Axitinib |
319460-85-0 |
WZ4002 |
1213269-23-8 |
Vandetanib |
443913-73-3 |
Sunitinib |
557795-19-4 |
Regorafenib |
755037-03-7 |
Imatinib |
152459-95-5 |
Foretinib |
849217-64-7 |
trametinib |
871700-17-3 |
Tivozanib |
475108-18-0 |
Pelitinib |
257933-82-7 |
Cediranib |
288383-20-0 |
Selumetinib |
606143-52-6 |
Tozasertib |
639089-54-6 |
CapMatinib |
1029712-80-8 |
Amuvatinib |
850879-09-3 |
Lestaurtinib |
111358-88-4 |
Brivanib |
649735-46-6 |
Â
1.The parcels will be sent within 24 hours once the order is verified.
2.Packaging is fully in accordance with customer demand.
3.There will be discounts whether you are an old customer or not.
To your satisfiction, here are our advantages
1.High quality and competetive price
1)we can offer coa certificate and official invoice.
2)we are manufacturer with own lab and factory, can provide high quality products with factory price.
3)products purity is test by our quality department strictly before sending, and you can also ask the third testing organization come and inspect, such as (sgs/ cti/ its), only after your confirmation will we send it out to you.
2.Fast and safe delivery
1)products can be sent out in 24 hours after payment.Tracking number available, fixed service person are 7x24h for you to contact.
2) secure and discreet shipment.Various transportation methods for your choice, like dhl/ups/tnt/fedex/sf-express.
3)customs pass and satisfied rate >99%.
4)for hot sale products we have stock in there for transferring.
3 we have clients throughout the world
1) professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2) market feedback and goods feedback will be appreciated, meeting customers' requirement is our responsibility.
3) high quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.
Ginseng Leaf Extract;Ginseng Berry Extract;Plant sterol ester;Hyaluronic Acid etc. can be widely used in Cosmetic industrial for skin care,
As a very professional supplier of cosmetic in China, we always give our customers best support with good quality in every field, we instant we will be your reliable partner and business support.
Hot Products:
Gingseng Leaf Extract UV80% Re 17% HPLC
Ginseng Berry Extract UV80% Re 20% HPLC
Plant sterol ester 70% from pine tree and soybean source
Sodium hyaluronate


Cosmetic
Cosmetic Raw Material,Leaf Extract,Panax Ginseng Berry Extract,Hyaluronic Acid
Excellent Health Products Co.,Ltd. , http://www.sino-excellent.com