Accurate medical development opportunities and challenges coexist: it is expected to lead a new era of medicine

At the moment, precision medicine is expected to lead a new era of medicine. "As an important direction for the development of the future big health industry, the realization of precision medicine based on big data, cognitive computing and other technologies, and the popularization of personal genetic sequencing are bringing great changes to the global health and medical industry." Recently, the Chinese Academy of Engineering, Zhan Qimin, director of the Peking University School of Medicine, said at the 6th Bio4P Precision Medical Innovation Forum and 2016 China Healthcare Innovation and Entrepreneurship Conference.

Accurate medical development opportunities and challenges coexist: it is expected to lead a new era of medicine

In fact, China attaches great importance to precision medicine. Gu Wei, a researcher in the era of the pharmaceutical industry, told the reporter of China Sankei Shimbun that the first meeting of experts on precision medical strategy was held in the Ministry of Science and Technology in 2015. It is proposed that 2030 yuan will be invested in the field of precision medicine for development by 2030. The industry. Moreover, "At present, China's major precision medicine special project has been approved, and has passed two reviews and implemented to more than 60 projects." Academician Chen Runsheng of the Chinese Academy of Sciences introduced at the 2016 China Health Information Technology Exchange Conference.

So, what exactly is precision medicine?

"Precise medicine is the application of modern genetic technology, molecular imaging technology, bio-information technology combined with patient living environment and clinical data to achieve accurate treatment and diagnosis, and develop personalized disease prevention and treatment programs." Zhan Qimin said that it is individualized Medical-based, new medical concepts and medical models developed with the rapid advancement of genome sequencing technology and the cross-application of bioinformatics and big data science.

"The focus of precision medicine is not on medical care, but on precision." Zhan Qimin stressed.

In short, precision medicine means that everyone is different. It is impossible to generalize the treatment. It is to be individual-centered, to subdivide patients from different dimensions, and then to prescribe the right medicine.

Applied to specific areas

As precision medicine is included in China's “13th Five-Year Plan”, Healthy China has upgraded to “National Strategy”.

"At present, precision treatment in China can be applied to molecular diagnosis, gene sequencing, cell therapy, medical robots and antibody drugs, which can be used as a sub-area of ​​precision medicine. At present, the overall concept of precision medical market is just innovative, if these five When the fields are put together, the overall scale of precision medicine will be formed." Gu Wei pointed out.

"Precise medicine is mainly used in 8 to 10 related diseases of rare diseases such as cancer, cardiovascular and cerebrovascular diseases and diabetes." Zhu Darong, a researcher at China Research Institute, said that the essence of precision medicine is through the genomics, proteomics and other frontier technologies and medical frontiers. Technology, for the analysis and identification, verification and application of biomarkers for large sample populations and specific disease types, so as to accurately find the cause of the disease and the target of treatment, and accurately classify the different states and processes of a disease. Ultimately, the purpose of personalized and precise treatment for diseases and specific patients can be achieved, and the benefits of disease diagnosis and treatment can be improved.

He Yiwu, senior vice president of Huada Gene Research Institute and head of global R&D of the group, said in an interview with the media that precision medicine is mainly used for early detection of cancer and targeted therapy, screening for birth defects of prenatal fetuses and diagnosis of rare diseases. . He analyzed lung cancer as an example. It is a very broad statement that a person has lung cancer. Because of the subdivision, lung cancer can be divided into many subtypes, each of which corresponds to different drugs and treatments, only through precise medical treatment. In order to find the most effective and symptomatic means.

"At present, the domestic focus on precision medicine is mainly concentrated in specific areas such as "non-invasive prenatal screening, tumor diagnosis and personalized treatment, genetic disease risk assessment and assisted reproduction, bioinformatics data analysis services", these are also genetic testing. You can immediately see the results in the field." An unnamed foreign drug company product manager Mr. Wang said in an interview with the reporter of China Sankei Shimbun.

It is worth noting that “the efficacy of some drugs in different populations is also very different. This is also related to genotypes. Some pharmaceutical companies are also seeking cooperation with medical institutions based on their own products. I think this will be precision medicine. The future direction of development." Mr. Wang added.

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