Latest report on cerebral palsy treatment: Cerebrolysin can increase social skills by 65%
Cerebral palsy in children is commonly called cerebral palsy, which refers to the group of clinical symptoms caused by non-progressive brain injury within one month after the birth of the newborn. The main clinical symptoms are motor and posture dysfunction, often accompanied by speech, cognition, hearing, visual impairment and epilepsy, as well as secondary muscle contraction and limb deformity injury, which are the most common causes of childhood disability. The global incidence of cerebral palsy in children is quite high, with 1-5 of every 1,000 live births suffering from cerebral palsy, and about 17 million people worldwide are affected by the disease. Prenatal and postnatal factors can lead to cerebral palsy, such as hypoxia, trauma, infection, genetic factors and developmental brain abnormalities. Cerebral palsy can be divided into sputum type, hand and foot sway type, tonic type, dysregulation type, tremor type, low muscle tone type and mixed type. Studies have shown that 3/4 of children with cerebral palsy are accompanied by pain; 1/2 are accompanied by mental retardation; 1/3 are unable to walk; 1/4 are unable to speak; 1/4 are associated with epilepsy; 1/10 It is blind. It can be seen that cerebral palsy has a huge impact on the individual, the medical environment and the social economy. The history of people fighting with the cerebral palsy dates back to the 1840s. At that time, John Little, an orthopaedic surgeon in the UK, took the lead in researching cerebral palsy. Since then, many treatment systems have been formed and developed over the past 100 years. In the second decade after the 21st century, with the rapid development and application of digital technology, more and more high-tech means of treating cerebral palsy have emerged. The author summarizes the current routine clinical treatments for cerebral palsy, as well as the latest digital solutions, to show you the promotion and support of science and technology for clinical care. General treatment of cerebral palsy Routine treatment of cerebral palsy is primarily directed to the management of its symptoms. Currently, medical institutions generally combine the use of medical interventions, rehabilitation, surgery, orthopedic devices and botulinum toxin A injections to improve patient function. It has long been believed that the central nervous system of the human body cannot be repaired once it is damaged. However, with the continuous development of medicine, the emergence of various methods of nerve recovery makes the repair of the central nervous system possible. These methods mainly include two types of neurodegenerative drugs and cell therapy. medical treatement Oxiracetam is a central nervous system drug that selectively affects the cerebral cortex and hippocampal neurons and contributes to the functional recovery of nerve cells. It activates glutamate receptors in the human brain and regulates the action of acetylcholine and glutamate. This increases the metabolic activity of nerve cells and can improve the learning ability, memory and daily activities of cerebral palsy patients. In general, the dosage of oxiracetam is 800-2400 mg / day, and gradually increase the dose after starting to take it. In a randomized, double-blind, controlled trial evaluating the efficacy and safety of oxiracetam in the treatment of cerebral palsy, 30 patients were enrolled in the drug. After 4 weeks of treatment, the patient's Wechsler Preschool Children's Intelligence Test Scale (WPPSI) scores both intelligence and activities of daily living were significantly improved. Cerebrolysin, nerve growth factor, ganglioside and lysine may also have potential therapeutic effects on early childhood cerebral palsy. Cerebrolysin is a neuropeptide with neurotrophic and neuroprotective effects. It inhibits apoptosis, increases synaptic plasticity, and induces neurogenesis; it also encourages the proliferation, differentiation, and migration of neural progenitor cells, leading to positive neurological prognosis. In a controlled study of 120 infants with severe perinatal brain injury, children were given intracerebral injection of cerebrolysin 0.1 mL / kg body weight twice a week for 5 weeks. The effectiveness of the intervention was assessed using the Communication and Symbolic Behavioral Development Scale (CSBS) baseline score. After 3 months, the social skills, speech, symbolic behavior, and total scores of the cerebral group increased by 65.44%, 45.54%, 358.06%, and 96.00%, respectively, from the baseline score. In addition, studies have given a case of cerebral palsy in children with acupoint injection of cerebrolys for 8 years, which also played a significant role in functional and cognitive improvement. The basic mechanism of action of gangliosides is similar to that of cerebrolysin. But in addition, it can play an important role in neurotransmission. In an experimental study, ganglioside GM1 was administered to neonatal rats with hypoxia-ischemia; after 26 days of treatment, the experimental group showed nerves in the suspension test, slope test, and open test compared with the control group. Behavioral function improvement. Dabepoetin and erythropoietin are also used as neuroprotective drugs. They have anti-inflammatory and anti-apoptotic properties that improve the cognitive function of infants. In a study involving premature babies, none of the infants who received erythropoietin developed cerebral palsy, compared with 5 in the placebo group. Cell therapy In the past decade, cell therapy has rapidly developed into a potential treatment for various neurological disorders including cerebral palsy. Medical workers use different types of cells to conduct experiments to study their benefits in cerebral palsy treatment. Many animal studies have demonstrated the efficacy of cell therapy in cerebral palsy, but there are currently few published human studies in this area. Here, we list several cell types used to treat cerebral palsy, as detailed below. Black Garlic,Fermented Black Garlic,Black Garlic Puree,Natural Fermented Black Garlic Powder shandong changrong international trade co.,ltd. , https://www.cragriculture.com