The next Nobel Prize? HKU announces successful development of new drugs to prevent and eliminate HIV
According to the website of the University of Hong Kong on April 26, a research team led by the Institute of Microbiology, Department of Microbiology, Li Ka Shing Faculty of Medicine, University of Hong Kong (Hong Kong University), developed a novel tandem bivalent broad-spectrum neutralizing antibody using genetic engineering technology. Bi-specific bNAb) effectively inhibits all tested AIDS strains and promotes the clearance of latently infected cells in humanized mice. The research has been published in the latest issue of the Journal of Clinical Research, one of the world's leading biomedical journals. According to reports, AIDS is currently a disease that cannot be cured. AIDS virus (HIV) has caused about 40 million deaths worldwide, and there are still about 36.9 million people living with HIV/AIDS. To curb the global pandemic of AIDS, it is important to develop effective AIDS vaccines or cures. However, the high mutation rate of HIV and the latent pool that antiviral drugs cannot be eliminated are still two major scientific challenges. Because it is extremely difficult to use a suitable antigen to induce a broad-spectrum neutralizing antibody (bNAb) that inhibits various AIDS variant viruses in the human body, passive immunization with the discovered bNAbs has become a practical method for HIV prevention and immunotherapy. (Observer Network)
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