Supported by many academicians, the International Sugar Group Research Center/International Polysaccharide Research Center was established.
On December 26th, the establishment ceremony and academic seminar of the International Sugar Group Research Center/International Polysaccharide Research Center was held in Shanghai International Medical Park. The project was jointly established by the Shanghai Institute of Materia Medica, Chinese Academy of Sciences and Shandong Zaozhuang New Zhongxing Co., Ltd., focusing on the research and development of precise diagnosis and treatment of sugar science. Academician of the Chinese Academy of Sciences, pharmaceutical chemist Chen Kaixian, academician of the Chinese Academy of Sciences, cell biologist Yan Gang, academician of Chinese Academy of Engineering, academician of the Academy of Developing Countries, Ding Jian, dean of the School of Pharmacy, Chinese Academy of Sciences, academician of the Chinese Academy of Sciences, basic theory of chromatography and new technology Zhang Yukui, a new method researcher, academician of the Chinese Academy of Sciences, professor of Wuhan University, doctoral tutor Zhang Yanna, deputy director of the Chinese Academy of Sciences Major Task Force Huang Tieqing, director of the Policy Coordination Division of the Biotechnology Development Center of the Ministry of Science and Technology of China, Yu Shanjiang, researcher of the Shanghai Institute of Materia Medica, Chinese Academy of Sciences Ding Wei, Director of the Biomedical Division of Shanghai Science and Technology Commission Cao Hongming, Deputy Director of Zhangjiang Administration of Shanghai Free Trade Zone Management Committee, Wu Jun, Deputy Secretary of Shanghai Zhangjiang (Group) Party Committee, Chairman of Shanghai International Medical Park Group Corporation, Wang Kairong, Zaozhuang Zhang Feng, director of the Municipal Food and Drug Administration, Song Haifang, deputy head of the Central Government of Zaozhuang City, Liu Xuedian, chairman and general manager of Zaozhuang Xinzhongxing, and Jinling, party secretary and other guests attended the unveiling ceremony. Research prospects and challenges in sugar science Polysaccharide is one of the most abundant substances in nature. It is widely found in animal cell membranes, plants and microbial cell walls. It is a kind of biological macromolecule closely related to human life and plays an important role in life-sustaining activities. In recent years, a large number of studies have shown that polysaccharides have many biological functions such as immune regulation, blood sugar lowering, blood lipid lowering, anti-tumor, anti-virus, anti-oxidation, anti-aging, anti-coagulation, anti-ulcer, anti-radiation and so on. With the development of glycomics and glycobiology, as well as the separation and purification of sugar, structural analysis, qualitative and quantitative analysis methods, more sugars with good pharmacological activity and very safe have entered the sugar scientists and pharmacists. Vision. At present, the most important drug for the treatment of Alzheimer's disease (AD), “Gal oligosaccharide (GV-971)â€, which is jointly developed by the Shanghai Institute of Materia Medica, Chinese Academy of Sciences, China Ocean University and Lugu Pharmaceutical, is a sugar drug. The latest results of research and development. Although polysaccharide research is getting more and more attention at present, due to the complex structure and function of carbohydrates, sugar chains can not be randomly synthesized and sequenced like nucleic acids and proteins, and lack of big data support of sugar groups, polysaccharide research also faces many problems. Academician Chen Kaixian said: "The basic scientific issues of exploring the links between sugar chain, disease and drugs have become a major scientific proposition in the frontier of life sciences. The complex and functional structure of carbohydrates is suitable for the treatment of complex diseases and is expected to lead to complex treatment. The frontier of innovation in disease." Academician of the Chinese Academy of Sciences, drug chemist Chen Kaixian Two "centers" were established to help the development of sugar science According to the introduction, the International Sugar Group Research Center/International Polysaccharide Research Center will cooperate with the international scope to understand the functions, biological activities, efficacy relationships, and mechanism of action of sugar groups and polysaccharides in tumors, neurodegenerative diseases and metabolic diseases. For the research direction, develop new concepts, new strategies, new technologies and new methods in the field of sugar science; use glycosides, sugar chemistry and glycobiology techniques to study glycans, glycoproteins and proteoglycans in life physiology and pathology The structure, function and biosynthesis of sugar chains provide a new way for the precise prevention and precision treatment of major diseases, promote the development of international sugar science, and lay a solid foundation for sugar science for human health. At the same time, it is a domestic and foreign scientific research institution, enterprise, public, sugar. Scientists provide sugar science technology and knowledge services to build academic exchanges and research platforms in the field of sugar and polysaccharides. Li Jia, deputy director of the Shanghai Institute of Materia Medica, Chinese Academy of Sciences, said: "China is a major resource for carbohydrates, and has made significant progress in the chemical synthesis of polysaccharides and the research on the efficacy of traditional Chinese medicines. Especially the first international AD. The successful completion of the clinical phase of the therapeutic and marine oligosaccharide GV-971 against Alzheimer's disease has promoted the research of international saccharide drugs, overcome the difficult problems of complex diseases in the world, and promoted the development of innovative drugs in China. The Institute of Pharmaceutical Research will also adhere to the spirit of continuous innovation, aiming at the frontier areas of international life science development and important scientific issues in drug research, conducting basic research and application of innovative drugs, and developing new theories, new methods and technologies for drug research. The center has made efforts to build." Li Jia, deputy director of Shanghai Institute of Materia Medica, Chinese Academy of Sciences Liu Xuedian, chairman and general manager of Zaozhuang New Zhongxing Company, said: “Science and technology innovation is the golden key to open the door to health. Zaozhuang New Zhongxing Company constantly adjusts the industrial structure and innovation mechanism system in the transformation of new and old kinetic energy, and takes the construction of the base as a carrier. Promote the development of green industry and actively explore new ways of combining science and technology with industry. The velvet planting base has realized the transformation from planting to processing of series products, and the products have entered the market of 17 cities in and outside the province. Complying with the country's advocacy of building a "healthy China" concept is the success of the close connection, deep integration, and advantages of various exhibitions. It is also the cooperation of all parties to rapidly transform scientific research results into productive forces and form a real economy industry. The reality model, we will take the opportunity of the establishment of the International Polysaccharide Research Center, based on the principle of long-term cooperation, mutual benefit and common development, give full play to its own advantages, strengthen the integration of capital and projects, and promote the collaborative innovation of science and technology and industry. Deep integration of innovation chain and industry chain to accelerate high-end biopharmaceuticals Industry velocity, biomedical science and technology to create new high ground, to build a beautiful China, Chinese health and make due contributions! " Liu Xuedian, Chairman and General Manager of Zaozhuang New Zhongxing Co., Ltd. Linking Zhangjiang Science City to build the International Polysaccharide/Sugar Group Research Center Wang Kairong, deputy secretary of Shanghai Zhangjiang (Group) Party Committee and chairman of Shanghai International Medical Park Group Corporation In response to the establishment of the International Sugar Group Research Center/International Polysaccharide Research Center, Wang Kairong, deputy secretary of Shanghai Zhangjiang (Group) Party Committee and chairman of Shanghai International Medical Park Group, said at the opening ceremony: “At present, Zhangjiang Science City and Shanghai International Medical Park are Focusing on the core carrying area for the development of Shanghai's health service industry, the Shanghai Asia Medical Center's iconic brand for foreign service strives to advance various tasks, including building a first-class cancer medical center in Asia, building a clinical trial hospital, and promoting third-party medical testing. The high-quality development, the whole industry chain of cell therapy from storage, research and development, production, transportation to treatment. International Sugar Group Research Center / International Polysaccharide Research Center settled in Shanghai International Medical Park, will be the innovative research and development of polysaccharide drugs in Zhangjiang Science City The field opens up new avenues to create new heights and will bring new hope to the treatment of many diseases." Academician Chen Kaixian said: "The center will be based in Shanghai International Medical Park, and strive to establish a world-class sugar science and sugar drug research and development center, try to strengthen cooperation with other international countries, and use Chinese as a polysaccharide, glycoprotein and proteoglycan. Research contributes." 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