UK breeds genetically engineered chickens against the H5N1 bird flu virus

British scientists are developing transgenic chickens against the H5N1 bird flu virus to cope with the long-term threat to human society from this highly pathogenic virus.
According to the British "The Times" report, this research was carried out by scientists from Cambridge University and Roslyn Institute in Scotland. Scientists have made chicken cells resistant to the H5N1 strain of bird flu by adding fragments of genetic material. Scientists are preparing to conduct similar experiments on eggs in a matter of weeks.
The report said that if this technique proves to be successful, it can also be used to breed transgenic chickens against other types of bird flu viruses.
Currently, scientists are experimenting with three methods: The first is to insert genes that control the production of the antiviral protein Mx into normal chicken cells to increase their resistance to H5N1 and other types of bird flu viruses. Many breeds of chickens This gene has defects; the second is the use of RNA (ribonucleotide) interference technology to interfere with the work of bird flu virus through RNA fragments, so that the chicken cells obtain the ability to resist multiple avian influenza viruses; the third method is to use RNA molecules. It induces the virus to replicate RNA instead of replicating itself. The scientists said that these three methods may be combined together in the future to jointly cultivate transgenic chickens.
However, experts also pointed out that even if this technology proves feasible, it will take several years before it can be put into practice. In the application process, the technology may encounter obstacles from the government regulatory agencies and public opinion.
The University of Cambridge professor Terry who is in charge of the study said that once the regulatory approval is obtained, it may take only 4 to 5 years. "We can replace chickens from all over the world with the type of transgenic (anti-H5N1 avian influenza virus)."

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