3D printing takes a big step toward artificial organ transplantation
Release date: 2016-04-27 Researchers report in the new issue of Nature Biotechnology that they use the newly developed 3D bioprinting system to print artificial ears, bones and muscle tissue that remain active after being transplanted into animals. This technology is still in the early stage of trial, and it may solve the problem of artificial organ transplantation after the future matures. At present, the organ tissues printed by 3D bio-printing technology are usually very unstable and too fragile in structure, and cannot be used for surgical transplantation. Because these products lack vascular structure and are small in size, even if transplanted, organs are not easily accessible. Oxygen and nutrients are hard to survive. In response to the above problems, the research team at the School of Regenerative Medicine at Wake Forest University in the United States has improved the existing 3D bioprinting technology and developed the "Organization and Organ Integrated Print System" (ITOP). This newly developed 3D bioprinting system combines water-based gels containing active human or animal cells with biodegradable polymeric materials as a printed material to help create stable structures in artificial organs. This system also prints many tiny channels like blood vessels in artificial organs. After organ tissue is transplanted into animals, oxygen and nutrients can be obtained through these channels, which is the key to ensuring survival after organ transplantation. After a while, blood vessels gradually grow in artificial organs, replacing microchannels. To verify the results, the researchers transplanted printed artificial ears, muscle fibers, and tibia into mice. After a period of time, these artificial organ tissues survived successfully and grew structures such as blood vessels and nerves. Anthony Atala, a scholar at the University of Wake Forest University's School of Regenerative Medicine, said that the combination of the two materials in the printing process and the tiny channels in the tissue structure provide appropriate for cell survival and tissue growth in artificial organs. surroundings. Another advantage of ITOP is the ability to tailor the organ tissue to be transplanted to patients through computed tomography and magnetic resonance imaging. For example, a patient needs to receive an ear transplant. This system can print a suitable artificial ear for transplantation based on imaging data. Source: Health News Roasted Pumpkin Seeds,Baking Pumpkin Seeds,Cooking Pumpkin Seeds,Toasted Pumpkin Seeds Wuyuan county dafeng oil food co.,ltd , https://www.dafengfood.com.cn