Let precision medicine take you into the era of smart medicine

In the era of intelligent medicine , the "doctor" who is with him may gradually enter the ordinary people's home. Scientists at the University of Bath in the United Kingdom have also recently developed a "discoloration bandage" to fight the pain. With the help of nanotechnology, the bandage can detect the wound and release the drug in time, and change the color to remind the patient whether a secondary infection occurs.

Let precision medicine take you into the era of smart medicine

British researchers have recently released this discolored bandage, which adds a gelatinous substance to the tiny envelope that releases a non-toxic fluorescent dye when it comes into contact with the flora that causes the infection.

Professor Toby Jenkins, the inventor of the University of Bath's Institute of Polymerization, invented the smart bandage. He said that this product can provide early warning of infection so that patients can find early treatment, but the product has not been tested by human body. However, Jenkins said that once the product is officially launched, we can completely get rid of antibiotics.

New "smart bandage"

Currently, Professor Jenkins' team is working with clinical researchers from the University of Bristol Pediatric Burn Center to focus on the application of smart bandages in the field of burn treatment. In traditional burn treatment, antibiotics are special drugs to prevent infection (especially for children), but antibiotics are used more and bacteria can develop resistance. However, the emergence of smart bandages can solve the problem of abuse of antibiotics, because it can accurately show the infection of the wound. In addition, it can monitor the infection of surgical wounds at any time.

But in the case of wounds, there will be bacterial parasites, some of which carry pathogens, but some are harmless, and the immune system can automatically remove them. But if the flora is too large, the immune system will be powerless, and we need human intervention. “The flora grows very quickly and can beat the immune system in just a few hours,” says Professor Jenkins, who can detect the infection in advance and set aside sufficient processing time for the doctor.

Professor Jenkins said that due to the presence of bacteria, a large number of bacteria secrete a special substance to protect against the immune system, and the immune system is often outnumbered. As the flora multiplies, its density will continue to expand, and the membrane will begin to produce toxins. The envelope of the intelligent bandage simulates the effect of the cell membrane, which attacks the toxin and releases the dye. These dyes diffuse and react with the gelatinous substance to fluoresce.

Let precision medicine take you into the era of smart medicine

The picture on the left is a bandage that is not exposed to bacterial toxins, and the picture on the right is a bandage covered with bacteria.

Keith Harding, an expert in wound healing in Cardiff University School of Medicine in the United Kingdom, said that although the clinical effects of the bandage have not been verified, it is definitely a major advancement in medicine and microbiology. After all, accurate diagnosis of wound infection is still in the medical world. A major challenge.

In the latest test, the smart bandage quickly began to fluoresce after exposure to the three pathogenic bacteria membranes, but for harmless bacteria, the bandages were “indifferent”. The team was also recognized by the British Medical Research Council for its contribution to the medical community. If it goes well, the smart bandage can enter the clinical testing phase in 2018.

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