Chinese researchers have found that stem cells are expected to treat premature ovarian failure
Chinese researchers reported in the US "Molecular Therapy" magazine on the 18th that animal experiments show that stem cell therapy is expected to safely treat premature ovarian failure. This brings new hope to some infertile patients. Premature ovarian failure refers to the phenomenon that the ovarian atrophy does not ovulate before the age of 40. At present, about 1% of women of childbearing age in the world have premature ovarian failure, which has become an important cause of female infertility. Several research groups are trying to help patients with premature ovarian failure by stimulating tissue regeneration or stem cell transplantation therapy. Professor Wu Ji from Shanghai Jiaotong University in China isolated female reproductive stem cells from one to two weeks old green fluorescent protein transgenic mice. After purification and culture, they were transplanted into mice with premature ovarian failure. Since this stem cell contains green fluorescent protein, it can emit green fluorescence under blue light excitation, so its post-transplant development can be observed by microscope. The transplanted stem cells migrate to the desired position in the body according to the body's needs, and are located in the stem cell nest of each tissue and organ. This process is called homing of stem cells. The results show that female germ stem cells have the same homing effect as other stem cells, and their nests are located on the near surface of the ovarian cortex, which is consistent with the expectations of Wu Ji et al. After the homing of female reproductive stem cells, some of the cells differentiate and gradually develop into mature oocytes, thereby restoring ovarian function. The researchers allowed mice transplanted with stem cells for 5 to 8 weeks to mate with adult male mice, producing offspring that express green fluorescent protein markers. Comparison with normal mice in the control group showed that the mice in both groups had the same developmental mechanism, and the mice with premature ovarian failure produced normal offspring. Dehydrated Onion,Dehydrated Onion Granules,Dehydrated Onion Powder,Dehydrated Onion Powder For Flavoring Xinghua Lvwei Foods Co.,Ltd , https://www.lvweifoods.com